Suitable for knee pain and osteoarthritis Hyaluronic Acid Injection TrHCROSS 2.0% is a stronger hyaluronic acid injection for people with knee osteoarthritis.

A hyaluronic acid injection is a treatment in which a gel-like substance naturally found in the body, hyaluronic acid, is injected directly into a joint, such as the knee. Normally, this substance is present in the joint fluid and provides lubrication and shock absorption. The injection is often used in osteoarthritis to improve joint function. This allows the joint to move more smoothly, and pain symptoms—such as those caused by knee osteoarthritis—often decrease.

De injectie wordt vaak toegepast bij artrose om de werking van het gewricht te verbeteren. Hierdoor kan het gewricht soepeler bewegen en nemen pijnklachten, zoals bij knieartrose, vaak af.

The injection is suitable for adults with knee osteoarthritis or chronic knee pain. Both younger and older patients may benefit from this treatment, provided there are no other medical restrictions.

Many people notice improvement within a few days to weeks. The effect may vary from person to person, but relief often lasts for several months.

Yes, TrHCROSS 2.0% is CE-certified and always administered under medical supervision. It contains high-quality, purified cross-linked hyaluronic acid, which is safely absorbed by the body.

Scientific research supports this treatment. A widely used method is the direct injection of hyaluronic acid into the joint. A study by del Olmo et al. (2023), entitled Resistance to enzymatic degradation and efficacy evaluation of crosslinked hyaluronic acid based commercial viscosupplements for knee osteoarthritis treatment, confirms that this therapy can provide several benefits.

👉 Read the full study here

After a hyaluronic acid injection, many people experience mild pain or discomfort for a few days. This is normal and temporary. The joint may feel sore or stiff for a short time, but these symptoms usually disappear within a few days. In rare cases, an infection can occur at the injection site. Watch for symptoms such as increasing pain, redness, swelling, or fever. If you develop a fever or symptoms worsen, contact your doctor immediately.

In zeldzame gevallen kan er een infectie ontstaan op de injectieplaats. Let dan op symptomen zoals toenemende pijn, roodheid, zwelling of koorts.

Krijgt u koorts of verergeren de klachten? Neem dan direct contact op met uw huisarts.

Yes, it is important that the injection is administered by a doctor or qualified healthcare professional. Your doctor can determine whether this treatment is suitable for you.

In many cases, a single injection is sufficient for long-lasting relief. Your doctor can advise if and when a repeat treatment is necessary.

In some cases, the treatment may be (partially) reimbursed. This depends on your insurance provider and policy. Please contact your insurer for details.

Een cortisone-injectie (ook wel corticosteroïdeninjectie genoemd) werkt snel ontstekingsremmend en pijnstillend. Het effect is vaak binnen enkele dagen merkbaar, maar houdt meestal maar enkele weken tot maanden aan. Cortisone kan op de lange termijn kraakbeen aantasten en wordt daarom beperkt aanbevolen.

A cortisone injection (also called a corticosteroid injection) provides rapid anti-inflammatory and pain-relieving effects. The effect is often noticeable within a few days but usually lasts only a few weeks to months. Long-term use of cortisone may damage cartilage, which is why it is recommended with caution.

A hyaluronic acid injection works differently: it restores the joint’s natural lubrication and helps absorb shocks. Its effect builds up more slowly (1–3 weeks) but can last much longer (up to 6 months or more). It is considered safer for long-term use, especially in mild to moderate knee osteoarthritis.

Several scientific studies have shown that hyaluronic acid injections can have a beneficial effect on joint problems. Especially in joints with mild to moderate wear, treatment has been proven to significantly reduce pain and stiffness. Joint mobility can also improve as a result.

In cases of severe joint degeneration, however, the benefit of hyaluronic acid injections has not yet been convincingly demonstrated. Research shows that in some patients the effect may last for up to 6 months after the injection.

Results vary from person to person. Unfortunately, the treatment does not work for everyone, and the degree of improvement can differ. It is not possible to predict in advance who will respond effectively to the injections.

A treatment that is increasingly being used is the direct injection of hyaluronic acid into the joint. A study by del Olmo et al. (2023), entitled Resistance to enzymatic degradation and efficacy evaluation of crosslinked hyaluronic acid based commercial viscosupplements for knee osteoarthritis treatment, confirms that this treatment can provide several benefits.
Read the full study here.